Barely Significant
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Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI.

Nat Commun · 2025 · PMC12125227 · PMID 40447634

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may be significantno p-value reported
This could be due to isotropic encoding measuring average ADC changes over all spatial directions (therefore including the smaller changes in diffusion parallel to fibres), in contrast with linear encoding measurements which may be significant only when maximally sensitive to fibres perpendicular to the diffusion encoding direction.

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