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A cowpea mosaic virus adjuvant conjugated to liposomes loaded with tumor cell lysates as an ovarian cancer vaccine.

Nat Commun · 2025 · PMC12125389 · PMID 40447608

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an increasing trendno p-value reported
With regard to the distribution of CD8 + T cells, there was no significant difference between the TCL-Lip−CPMV and TCL-Lip + CPMV groups, but there was an increasing trend in the overall number of CD8 + T cells and the proportions of CD44 + memory T cells, CD44 + CD62L – effector memory T cells, CD44 + CD62L + central memory T cells, and CD69 + activated T cells in the following sequence: HEPES → TCL-Lip → CPMV → TCL-Lip + CPMV → TCL-Lip–CPMV (Fig. 4f–j ).

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