borderline significantp < 0.06
The only study to report shear rate found a borderline significant ( p < 0.06) difference in this metric between PCOS and controls (Berbrier et al., 2023 ), but given the large impairment in FMD seen in PCOS, it is unlikely that this is fully explained by differences in shear, and it is unclear how androgens might impact the shear stimulus.