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Comprehensive single-cell analysis deciphered the immunoregulatory mechanism of TPPU in alleviating sepsis-related acute liver injury.

J Adv Res · 2025 · PMC12126731 · PMID 39956402

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a decreasing trendno p-value reported
Comparative analysis with the control group revealed a decreasing trend in the percentage of M1-like macrophages and monocytes in the TPPU group, alongside a significant increase in M2-like macrophages ( Fig. 5 H and I).

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