Longitudinal analysis of step counts in Parkinson's disease patients: insights from a web-based application and generalized additive model.

We observe that several variables, including sex ( p -value = 0.03), handedness ( p -value = 0.015), PD status of the father ( p -value = 0.056, close to the significance level), COVID-19 status ( p -value = 0.008), cohort ( p -value < 0.0001), as well as the smoothing curve on age ( p -value < 0.0001), and the random effect of the smoothing trajectory on age ( p -value =0.0001), all demonstrate statistical significance or are close to significance in relation to step counts, except for the PD status of the mother ( p -value = 0.47).

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