TRAIL (DR5) receptor and the modulation of TRAIL pathway in PLWHIV: key mechanisms in the progression of HIV disease.

BMC Mol Cell Biol · 2025 · PMC12128504 · PMID 40452022

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

an increasing trendno p-value reported

It should be noted that this is the first study that evaluates the expression of TRAIL in cells from PLWHIV before ART, and interestingly it was observed a significant elevation of DR5 expression on CD14 + CD4 + monocytes and CD3 + CD4 + T-cells of PLWHIV although in the last population there was only an increasing trend.

also in 25,605 other papers

very close to significanceno p-value reported

Some of our results show a trend, and p-value is certainly very close to significance.

also in 54 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.