Barely Significant
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Anti-inflammatory effect of fluvastatin on polarized macrophages and its dependence on the mevalonate pathway.

Sci Rep · 2025 · PMC12130524 · PMID 40456744

Europe PMCDOI
1
hedged sentence
0.0720
closest p · 1.4× alpha
0.0720
boldest claim

The sentences

borderline significantp = 0.072so close (0.05 < p ≤ 0.1)
A key finding of our study is the significant reduction in pro-inflammatory genes (NFκB, IL-1β, IL-6, TNFα and iNOS expression by M1 macrophages after fluvastatin treatment, MCP-1 expression was also reduced, though this reduction was borderline significant ( p = 0.072).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.