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Taurine Alleviates Pancreatic β-Cell Senescence by Inhibition of p53 Pathway.

J Diabetes · 2025 · PMC12130737 · PMID 40458841

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Interestingly, serum taurine levels in aged mice exhibited a decreasing trend (Figure 1F ), indicating a potential increase in taurine uptake or intracellular taurine biosynthesis in pancreatic islets under aging conditions. 3.2 Taurine Supplementation Alleviates β‐Cell Inflammation and Senescence in Age‐and Drug‐Induced Models Ex Vivo and In Vitro To explore whether taurine exerts beneficial effects on β‐cells under aging conditions, we employed different ex vivo and in vitro approaches.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.