MDA5 variants trade antiviral activity for protection from autoimmune disease.

BMC Med Genomics · 2025 · PMC12131765 · PMID 40457382

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marginal significanceno p-value reported

The significance of the associations varied across diseases, with T1D and hypothyroidism showing the highest significance, whereas Crohn’s disease and psoriasis showed marginal significance for some variants.

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