Barely Significant
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Global, regional, and national burdens of <i>Clostridioides difficile</i> infection over recent decades: a trend analysis informed by the Global Burden of Disease Study.

Microbiol Spectr · 2025 · PMC12131777 · PMID 40272190

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an increasing trendno p-value reported
Globally, the overall ASDR and ASMR of CDI showed an increasing trend (AAPC ASDR = 1.39, 95% CI: 1.23–1.55; AAPC ASMR = 2.79, 95% CI: 2.66–2.93).

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