Forebrain neural progenitors effectively integrate into host brain circuits and improve neural function after ischemic stroke.

Over time, the expression of TBR1 decreased (28% ± 10%), whereas BRN2 (41% ± 5%) and SATB2 (40% ± 8%) showed an increasing trend, ultimately resulting in relatively balanced distribution of deep and superficial layer neurons within this system (Fig. 2a and Supplementary Fig. 4b ), in contrast to many differentiation protocols that result in reduced production of upper-layer neurons.

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