Comparative evaluation of nano ocular delivery systems loaded pH and thermosensitive in situ gels for Acanthamoeba keratitis treatment.

Reduction in the number of amoeba treated by different PI formulas compared to parasite control After 24 h of incubation, the PI chitosan nanoparticles gel demonstrated a 92% reduction in the number of viable amoebae, which was extremely significant when compared to the parasite control followed by PI gel, PI NLC Gel, PI LPs Gel, and commercial PI Eye drops (Table 5 ).

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