Bioceramics-enhanced patch activates epicardial epithelial-to-mesenchymal transition via Notch pathway for cardiac repair.

Sci Adv · 2025 · PMC12136047 · PMID 40465713

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an increasing trendno p-value reported

In contrast, the genes in cluster 2 were down-regulated after MI, which displayed an increasing trend after different therapeutic treatments, and the GelMA-4LMS ECP group showed the highest increase compared with that in the MI group.

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a decreasing trendno p-value reported

With different therapeutic treatments, the expression of these genes showed a decreasing trend, and the GelMA-4LMS ECP group exhibited the largest down-regulation in gene expression, which converged toward the sham group.

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