KinaseFusionDB: an integrative knowledge of kinase fusion proteins in multi-scales.

Brief Bioinform · 2025 · PMC12140011 · PMID 40471992

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highly significantP < .001actually significant

Notably, ABL1, ALK, and BCR of BCR-ABL1 in leukemia and EML-ALK in lung cancer showed highly significant fold changes ( P < .001) in their cancer types, directly showing the impact of kinase fusion genes to enhance the oncogenic function of kinases.

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