Overflow metabolism originates from growth optimization and cell heterogeneity.

Elife · 2025 · PMC12140630 · PMID 40472190

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an overall trendno p-value reported

ribosomes not bound to mRNAs) may vary with culturing conditions ( Dai et al., 2017 ; Li et al., 2018 ) and between individual cells within the same culture ( Pavlou et al., 2025 ), despite an overall trend toward growth optimization.

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