Comparative analysis of liver cancer burden trends in China and worldwide between 1990 and 2021.

Front Public Health · 2025 · PMC12141300 · PMID 40487524

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a decreasing trendno p-value reported

An increasing trend was defined by an AAPC with a 95% CI greater than 0, a decreasing trend by a 95% CI less than 0, and a stable trend if the CI included 0 ( 18 ).

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an increasing trendno p-value reported

However, an increasing trend has been observed in regions with historically low incidence rates, such as the United States ( 8 , 9 ), highlighting the need for strengthened prevention and control measures against liver cancer.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.