Irregularities in the IARC Working Group Evaluation of Ramazzini Institute Aspartame Studies.

Ann Glob Health · 2025 · PMC12143253 · PMID 40487707

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a positive trendno p-value reported

In males, a re‐analysis of the above [study] data indicated a significant increase in the incidence of monocytic leukaemia, histiocytic sarcoma, and a positive trend in the incidence of total myeloid tumours at all doses.” In transplacental and perinatal [RI] exposure studies in male rats, aspartame “caused malignant schwannoma and in female rats, aspartame caused mammary gland carcinoma and renal pelvis papilloma.

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