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Temporal Trend in Selective Cyclooxygenase-2 Inhibitors Sales in Brazilian Drugstores.

Pharmacoepidemiol Drug Saf · 2025 · PMC12144667 · PMID 40481681

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an increasing trendno p-value reported
The consumption of etoricoxib also exhibited an increasing trend, which was not consistent and presented structural breaks nationally and in most Brazilian regions during this period, with higher consumption in the South and Midwest regions.

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