Barely Significant
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Effects of Tirzepatide on Patients With Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Retrospective Cohort Study.

Cureus · 2025 · PMC12145500 · PMID 40486301

2
hedged sentences
0.0640
closest p · 1.3× alpha
0.0640
boldest claim

The sentences

a trend toward significancep = 0.064so close (0.05 < p ≤ 0.1)
showed a trendp = 0.064so close (0.05 < p ≤ 0.1)
While neither factor reached statistical significance in the multiple regression model, age before the switch showed a trend toward significance as a potential predictor of fatty liver index reduction (p = 0.064).

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may be significantno p-value reported
Therefore, our finding that the concomitant use of an SGLT2i does not suppress the therapeutic effects of tirzepatide may be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.