A strategy for liver selective NRF2 induction via cytochrome P450-activated prodrugs with low activity in hypoxia.

J Biol Chem · 2025 · PMC12145549 · PMID 40209947

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highly significantno p-value reported

Importantly, the difference in the effect of the 3-methylphenol prodrug in CYP3A4 transfected compared to control cells was highly significant ( Fig. 6 C ).

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