Elevation of p53 sensitizes obese kidney to adriamycin-induced aberrant lipid homeostasis via repressing HNF4α-mediated FGF21 sensitivity.

J Adv Res · 2025 · PMC12147646 · PMID 39019110

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highly significantno p-value reported

However, a highly significant positive correlation has been observed between the elevation of serum FGF21 and obesity [15] , [16] , which may be illustrated by an expiatory response or resistance to FGF21.

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