The expression change for autosomes after transgene induction is barely significant; and it was not clear what was used as the Ctrl?
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<i>Xist</i> RNA binds select autosomal genes and depends on Repeat B to regulate their expression.
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The sentences
This effect leads to clear sex difference - where female cells express the ~100 or so autosomal genes at a lower level than male cells (Figure 7H)." This sweeping statement fails to include that in MEFs there is no significant expression difference, in transgenics only borderline significance, and at d14 no significant expression difference.