Barely Significant
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Systematic Investigation of Impact of Antifoam and Extracellular Vesicles on Fouling of Hollow Fiber Filters in Intensified Perfusion Processes Highlights the Key Impact of Antifoam.

Biotechnol Bioeng · 2025 · PMC12152464 · PMID 40235351

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might be significantno p-value reported
Since significant filter fouling impacts with 10,000 g and 100,000 g pellet fractions in the offline small‐scale model were seen at spike concentrations > 4X, the antifoam concentrations in the spiking studies might be significant (> 20−100 ppm).

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