Evolutionary dynamics of predicted G-quadruplexes in human and other great apes.

Genome Biol · 2025 · PMC12153182 · PMID 40500762

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a positive trendno p-value reported

While this enrichment decreased after correcting for GC content, a positive trend suggests a connection between G4s and replication origins, particularly in more highly conserved G4s as opposed to human-specific ones.

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