Barely Significant
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Free Flap Salvage Using Extracorporeal Tissue Plasminogen Activator Administration: A Comparative Study.

Plast Reconstr Surg Glob Open · 2025 · PMC12153280 · PMID 40502428

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a positive trendno p-value reported
4 , 6 , 7 Rinker et al 4 found a positive trend toward the use of tPA, with 67% of the flaps with a pedicle thrombosis receiving tPA being salvaged, compared with 29% of the flaps not receiving tPA.

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