Identification of an Immune-Related Gene Signature for Prognostic Prediction in Glioblastoma: Insights from Integrated Bulk and Single-Cell RNA Sequencing.

Cancers (Basel) · 2025 · PMC12153616 · PMID 40507280

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hedged sentence

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closest p · 1.1× alpha

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boldest claim

The sentences

a trend toward significancep = 0.055so close (0.05 < p ≤ 0.1)

Further Cox regression analyses, performed using the TCGA dataset, revealed a significant association between the gene signature and patient outcomes: four out of the five genes were independently associated with survival ( p < 0.05; hazard ratios ranging from 1.48 to 1.54), while MS4A6A showed a trend toward significance ( p = 0.055, HR = 1.4).

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