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Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels.

Cells · 2025 · PMC12154489 · PMID 40498008

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an increasing trendno p-value reported
Hypoxia Benefits the Maintenance of bSCs We conducted enrichment analysis on genes associated with stem cell self-renewal identified through transcriptomic sequencing, generating a heatmap and GSEA results ( Figure S2A,B ), which revealed an increasing trend of pluripotency-related gene expression in the hypoxia group.

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