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Global, regional, and national trends in pulmonary arterial hypertension burden, 1990-2021: findings from the global burden of disease study 2021.

Front Public Health · 2025 · PMC12158705 · PMID 40510578

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an increasing trendno p-value reported
Furthermore, Central Asia was the only region showing an increasing trend.

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a decreasing trendno p-value reported
The age-standardized mortality rate (ASMR) was 0.27 per 100,000 persons (95% UI: 0.23–0.32), with an EAPC of −0.57 (95% CI: −0.72 to −0.42), indicating a decreasing trend in ASMR ( Table 2 ; Figure 1B ).

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