Barely Significant
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Comparative evaluation of efficacy and safety of nitrous oxide and midazolam for conscious sedation in pediatric dental patients: a systematic review and meta-analysis.

J Dent Anesth Pain Med · 2025 · PMC12160028 · PMID 40521429

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a slight trendno p-value reported
(4) Interpretation: • While the pooled effect suggests a slight trend toward Midazolam being more effective in reducing anxiety, the result was not statistically significant because of the large variability. • Clinically, the choice between Midazolam and Nitrous Oxide may depend on individual patient factors and the procedural context.

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