ITLN1 exacerbates Crohn's colitis by driving ZBP1-dependent PANoptosis in intestinal epithelial cells through antagonizing TRIM8-mediated CAPN2 ubiquitination.

Int J Biol Sci · 2025 · PMC12160931 · PMID 40520022

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an increasing trendno p-value reported

However, recent data indicate an increasing trend in the incidence of CD in China, especially in major cities 3 .

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