If the AAPC value and its lower boundary of 95% CI were both >0, an increasing trend of rates was deemed.
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Global burden attributed to alcohol and drug use among adolescents and young adults, 1990-2019: results from the Global Burden of Disease Study 2019.
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The sentences
In contrast, if the AAPC and its upper boundary of 95% CI were both <0, a decreasing trend of rates was deemed.