Role of diet, physical activity and new drugs in the primary management of cancer cachexia in gastrointestinal tumors - a comprehensive review.

Front Oncol · 2025 · PMC12162283 · PMID 40519290

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a favorable trendno p-value reported

In patients with advanced cancer engaging in moderate exercise, a favorable trend was observed in inflammatory markers, with stabilization or slight reduction of IL-6 and CRP levels compared to sedentary controls (though results did not always reach statistical significance due to small sample sizes).

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a positive trendno p-value reported

A systematic review in 2023 (12 controlled studies, including 9 RCTs) reported that approximately 75% of examined outcomes showed a positive trend in body weight or composition (lean/fat mass) in patients who engaged in exercise ( 78 ).

also in 5,550 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.