Predictive and prognostic value of the neutrophil-to-lymphocyte ratio for acute kidney injury: a systematic review and meta-analysis.

Clin Exp Med · 2025 · PMC12165981 · PMID 40512416

Europe PMC DOI

hedged sentences

0.0535

closest p · 1.1× alpha

0.0535

boldest claim

The sentences

marginal significancep = 0.0535so close (0.05 < p ≤ 0.1)

S7 , the low NLR cutoff subgroup exhibited predictive value for AKI (OR 1.526, 95% CI 1.38–1.68, p < 0.001) without significant inter-study heterogenicity ( I 2 = 29.1%), whereas the high-cutoff group showed limited predictive utility with marginal significance (OR 1.334, 95% CI 1.00–1.79, p = 0.0535) and the heterogenicity in this subgroup remained significant ( I 2 = 93%).

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borderline significanceno p-value reported

However, NLR showed limited predictive value with borderline significance in the subgroup with high NLR cutoff values.

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