Similarly, when examining the changes in genes involved in Wnt signaling ( Wnt3 , Ctnnb1 , Tcf4 , Tcf7l2 ), the expression of Wnt3 and β-catenin ( Ctnnb1 ) showed an increasing trend, but these changes were not significant (Fig. 4b ).
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Exercise alters transcriptional profiles of senescence and gut barrier integrity in intestinal crypts of aging mice.
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