Sestrin2 alleviates cognitive impairment via inhibiting hippocampus ferroptosis in cigarette smoke-induced chronic obstructive pulmonary disease.

Compared to controls, CS-exposed mice showed a decreasing trend in the number of arm entries ( Fig. 2 H) and a decrease in the percentage of spontaneous alternations ( Fig. 2 I), suggesting that COPD mice exhibit spatial memory impairment.

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