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Clinical proof-of-concept results with a novel TRPA1 antagonist (LY3526318) in 3 chronic pain states.

Pain · 2024 · PMC12168806 · PMID 39679712

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a numerical trendno p-value reported
Taken together with the analysis of the primary endpoint in Table 3 , these results show that there is a numerical trend of continuous improvement in pain (API-NRS) from baseline to week 6 and a stabilization of the response between 6 and 8 weeks (ie, no additional improvement in pain intensity) in the LY3526318 arm, while the response to placebo shows continuous improvement.

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