Higher levels of D2R and D3R in the frontal-striatal regions are associated with reduced perseverative reward seeking after opioid abstinence.

Front Behav Neurosci · 2025 · PMC12171296 · PMID 40529937

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a trend toward significanceno p-value reported

The ANOVA showed a significant difference in D2R levels in the mPFC among groups [ F (2, 14) = 4.01, p = 0.042], but post hoc analyses only revealed the differences with a trend toward significance between saline- and morphine-treated groups (SAL vs.

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