Coconut oil derived medium-chain triglycerides ameliorated memory deficits via promoting neurite outgrowth and maintaining gut homeostasis in 5×FAD mice.

Front Nutr · 2025 · PMC12171442 · PMID 40529430

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an increasing trendno p-value reported

In contrast, MCT intervention dramatically increased the number of hippocampal neurons, while RBDCO treatment showed an increasing trend in neuron numbers compared to the vehicle-treated 5×FAD mice ( Figures 3A , B ).

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a decreasing trendno p-value reported

In contrast, MCT intervention markedly reduced Aβ deposition in the hippocampal region, while RBDCO treatment showed a decreasing trend in Aβ plaques.

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