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Clinical efficacy of different therapeutic options for knee osteoarthritis: A network meta-analysis based on randomized clinical trials.

PLoS One · 2025 · PMC12176148 · PMID 40531843

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a decreasing trendno p-value reported
an increasing trendno p-value reported
The study observed an increasing trend in prevalence among individuals under 35 years of age, suggesting a decreasing trend in the age of onset for knee osteoarthritis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.