a decreasing trendP < 0.001
an increasing trendP < 0.001
During the same period, there was an increasing trend of HPV infection in the proportion of patients under 35 years of age (Z = 4.784, P < 0.001), a decreasing trend among those aged 36 to 64 years (Z=-4.689, P < 0.001), and no significant change in the proportion of patients aged 65 years and older (Z=-0.378, P = 0.705) (Fig. 2 -A).