Vitamin D and omega-3 fatty acids attenuate MSG-induced neurodegeneration by modulating tau pathology, neuroinflammation, and VDR expression in rats.

These findings were confirmed via statistical analysis of the percentage of degenerated neurons per 500 cells within the hippocampus, where one-way ANOVA demonstrated a highly significant effect on apoptotic cell counts across experimental groups ( F(4 , 10) = 380.1, P < 0.001), This exceptionally large F-statistic underscores the pronounced treatment-induced modulation of apoptotic mechanisms between groups.

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