The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy.

Elife · 2025 · PMC12187132 · PMID 40552710

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partial significanceno p-value reported

Regarding the importance of triadic interactions for the molecular function of the ULK complex, we observed their partial significance for ULK1 kinase activity against ATG14, a component of PI3KC3-C1, in our assays ( Figure 4—figure supplement 1D, E ).

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