Cardiometabolic Risk Marker Changes in Centrally Obese Women Using Depot Medroxyprogesterone Acetate (DMPA) in Kigali, Rwanda.

These findings agree with those of a similar prospective study conducted in India among postpartum women, which reported a progressive increase in serum TG, LDL-c, and TC and a decrease in HDL-c in DMPA users.[ 24 ] However, there is some discordance with findings from a study conducted in Nigeria, which reported an increase in serum LDL-c and a decrease in HDL-c but no change in TC and TG when comparing the baseline results and the results obtained after three months of DMPA use.[ 37 ] Similarly, a study conducted among Nepalese women indicated that after two years of DMPA use, there was a highly significant increase in TC and LDL-c, with no significant changes observed in TG and HDL-C.

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