The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions.

J Biol Chem · 2025 · PMC12192683 · PMID 40349772

Europe PMC DOI

hedged sentence

0.0864

closest p · 1.7× alpha

0.0864

boldest claim

The sentences

a trend toward significancep = 0.0864so close (0.05 < p ≤ 0.1)

We note that co-expression of LRP1 with ACE2 increases internalization of S1 subunit but does not significantly increase surface association, although there is a trend toward significance ( p = 0.0864).

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