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Modulation of TvRAD51 Recombinase in <i>Trichomonas vaginalis</i> by Zinc and Cadmium as a Potential Mechanism for Genotoxic Stress Response.

Pathogens · 2025 · PMC12195773 · PMID 40559573

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highly significantno p-value reported
The Gene Ontology (GO) enrichment analysis showed a significant association with biological processes such as DNA metabolic processes, DSB break repair, and DNA recombination, and metabolic functions such as catalytic activity and ATP-dependent DNA damage sensing and acting activity, mainly in the MRE11 complex, a multi-subunit nuclease that is composed with RAD50 and Nbs1/Xrs2, and is involved in checkpoint signaling and DNA replication, mainly in nucleus with highly significant FDR values ( Figure 3 B).

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