Barely Significant
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Effect of <i>CYP1A2</i>, <i>CYP2D6</i>, and <i>CYP3A4</i> Variation on Antipsychotic Treatment Outcomes.

Pharmaceuticals (Basel) · 2025 · PMC12196257 · PMID 40573287

Europe PMCDOI
1
hedged sentence
0.0751
closest p · 1.5× alpha
0.0751
boldest claim

The sentences

a trend towards significancep = 0.0751so close (0.05 < p ≤ 0.1)
There was no significant effect of reduced CYP3A4 activity, but there was a trend towards significance (mean difference: 6.242; 95% CI: −0.612, 13.095; p = 0.0751), where reduced metabolisers reported more adverse drug reactions than normal metabolisers.

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