Low-density lipoprotein cholesterol levels and in-hospital bleeding in patients with atrial fibrillation: findings from CCC-AF project.

Front Cardiovasc Med · 2025 · PMC12199265 · PMID 40574812

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an increasing trendno p-value reported

By comparing each endpoint of the LDL-C groups (lower than the endpoint with higher as a reference), we found an increasing trend for bleeding with a steady increase in risk at LDL-C levels below 70 mg/dl.

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a decreasing trendno p-value reported

Meanwhile, an opposite trend was found for ischemic events, with a decreasing trend of risk at LDL-C levels <70 mg/dl, and this stopped being significant when the LDL-C levels reached ≥70 mg/dl ( Figure 2 ).

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