Global, regional, and national burden of leukemia: Epidemiological trends analysis from 1990 to 2021.

PLoS One · 2025 · PMC12200851 · PMID 40569983

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an increasing trendno p-value reported

In contrast, 28 countries showed an increasing trend, especially Lesotho, Zimbabwe and Chad, with EAPC of 2.53 (95% CI: -0.09 to 5.22), 2.21 (95% CI: -0.49 to 4.98) and 1.53 (95% CI: -0.31 to 3.4), see S2 Table .

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a decreasing trendno p-value reported

There was a decreasing trend in leukemia incidence across all regions, most notably in Oceania (EAPC =-1.75, 95% CI: -4.35 to 0.92), followed by Central Asia and High-income North America, with EAPCs of -1.05 (95% CI: -2.26 to 0.18) and -1.04 (95% CI: -2.7 to 0.64), see S1 Table .

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