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γδ<sup>+</sup> T-cell-derived IL-17A stimulates airway epithelial/stromal cells to secrete G-CSF, promoting lung-specific pathogenic Siglec-F<sup>+</sup> neutrophil development in PPE-induced emphysema.

Cell Mol Immunol · 2025 · PMC12206919 · PMID 40461699

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a decreasing trendno p-value reported
The results revealed a decreasing trend in the Siglec-F+ neutrophil population, although the reduction was less pronounced than that observed with anti–IL-17A antibody treatment (Fig.

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