Reassessing the relationship between major depressive disorder and blood lipids: a comprehensive Mendelian randomisation study.

In the East Asian population, the association was directionally consistent and marginally significant (OR: 1.085, 95% CI 0.986 to 1.193, p=0.094; table 1 and online supplemental table 3 ).

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However, genes in MDD–WHR discordant subsets, WHR–TG concordant subsets and MDD–TG concordant subsets were all highly significant in the assembling and organisation process of nucleosomes, chromatin and protein–DNA complexes ( onlinesupplemental figures 3 5 ).

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